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Nutrition HubStrong EvidenceActionability: High

Lactose Persistence

The evolutionary genetics of the LCT gene and genetic markers associated with lactase enzyme persistence into adulthood.

Biological Mechanism & Scientific Context

Lactase non-persistence is the ancestral human baseline. Regulatory variants upstream of the LCT gene (in MCM6) enable persistent lactase synthesis throughout adult life, determining tolerance to unfermented dairy products.

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